BMS-1166 hydrochloride

Overview

BMS-1166 hydrochloride is a potent PD-1/PD-L1 immune checkpoint inhibitor. BMS-1166 hydrochloride induces dimerization of PD-L1 and blocks its interaction with PD-1 , with an IC 50 of 1.4 nM. BMS-1166 hydrochloride antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation.

Application

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Product Information

• Catalog No.: HY-102011A
• CAS No.: 2113650-05-6
• Molecular Formula: C36H34Cl2N2O7
• Molecular Weight: 677.57
• Purity: 99.31%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (3.69 mM); Clear solution
• Availability: In-stock

Source

Original product source