WM-1119, a chemical probe, is a highly potent and selective KAT6A inhibitor, with an IC 50 of 0.25 μM for KAT6A in lymphoma cells, the binding K D values of WM-1119 with KAT6A, KAT5 and KAT7 are 2 nM, 2.2 μM, 0.5 μM , respectively.
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