3MB-PP1

Overview

3MB-PP1, a bulky purine analog, is a Polo-like kinase 1 ( Plk1 ) inhibitor. 3MB-PP1 blocks mitotic progression and cell division arise through target Plk1 in in cells expressing analog-sensitive Plk1 alleles. 3MB-PP1 specifically inhibits the activity of analog-sensitive Ssn3 ( Cdk8 ). 3MB-PP1 inhibits Leu93 Mutant Zipper-interacting protein kinase ( Leu93-ZIPK ; IC 50 =2 μM). 3MB-PP1 can be used for the research of hypha formation of Candida albicans and cell division.

Application

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Product Information

• Catalog No.: HY-102069
• CAS No.: 956025-83-5
• Molecular Formula: C17H21N5
• Molecular Weight: 295.38
• Purity: 99.66%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (8.46 mM); Clear solution
• Availability: In-stock

Source

Original product source