EZ-482

Overview

EZ-482, a novel ligand of apolipoprotein ( apoE ) , binds to sites on apoE in the C-terminal domain with K d s of 5-10 μM for apoE3 and apoE4. EZ-482 binds to apoE4 by a unique N-terminal allosteric effect. EZ482 has the potential for Alzheimer’s diseas.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Alzheimer's Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Apolipoprotein

Product Information

• Catalog No.: HY-103076
• CAS No.: 1016456-76-0
• Molecular Formula: C23H19ClN4O5S
• Molecular Weight: 498.94
• Purity: 97.21%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.08 mg/mL (4.17 mM); Clear solution
• Availability: In-stock

Source

Original product source