Melperone hydrochloride

CAS No.：1622-79-3
Grade：99.98%
Formula：C16H23ClFNO
M.W.：299.81

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Overview

Melperone hydrochloride is a butyrophenone with atypical antipsychotic properties. Melperone hydrochloride is a multireceptor antagonist with K d s of 102 nM, 180 nM, 180 nM, and 150 nM for 5-HT2A , dopamine D2 , α1-adrenergic , and α2-adrenergic receptors , respectively. Melperone hydrochloride has weak binding to histamine H1, 5-HT2C, 5-HT1A, 5-HT1D, and muscarinic receptors, with K d values of 580 nM, 2100 nM, 2200 nM, 3400 nM, >10000 nM, respectively. Melperone hydrochloride is also a CYP2D6 inhibitor. Melperone hydrochloride can be used for the study of schizophrenia, and agitation in the elderly.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > 5-HT Receptor | Products > Signaling Pathways > Dopamine Receptor | Products > Signaling Pathways > Adrenergic Receptor | Products > Signaling Pathways > Cytochrome P450

Product Information

Catalog No.: HY-103109
CAS No.: 1622-79-3
Molecular Formula: C16H23ClFNO
Molecular Weight: 299.81
Purity: 99.98%
Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
Availability: In-stock

Source

Original product source

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