DOI hydrochloride is a serotonin 5-HT 2A / 2C receptor agonist with K i values of 0.7 nM, 2.4 nM and 20 nM for h5-HT 2A , h5-HT 2C and h5-HT 2B receptors, respectively. DOI hydrochloride can across the blood-brain barrier. DOI hydrochloride increases head twitches in mice.
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