PNU-142633 is a high affinity, selective and orally active 5-HT 1D receptor agonist with K i s of 6 nM and > 18 000 nM for human 5-HT 1D receptor and human 5-HT 1B receptor, respectively. PNU-142633 has anti-migraine efficacy.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > 5-HT Receptor
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