BAY 60-6583

Overview

BAY 60-6583 is a potent and high-affinity agonist of adenosine A 2B receptor ( EC 50 =3 nM) over A1, A2A, and A3 receptors. BAY 60-6583 binds to mouse, rabbit, and dog A2BAR with K i values of 750 nM, 340 nM and 330 nM, respectively. BAY 60-6583 has a cardioprotective effect in a myocardial ischemia model.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Adenosine Receptor

Product Information

• Catalog No.: HY-103171
• CAS No.: 910487-58-0
• Molecular Formula: C19H17N5O2S
• Molecular Weight: 379.44
• Purity: 99.67%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 4.17 mg/mL (10.99 mM); Clear solution
• Availability: In-stock

Source

Original product source