PSB-06126 is a selective nucleoside triphosphate diphosphohydrolase ( NTPDase ) inhibitor, with the K i values of 0.33 μM for rat NTPDase 1, 19.1 μM for NTPDase 2 and 2.22 μM for NTPDase 3, respectively. PSB-06126 acts on human NTPDase 3 with an IC 50 value of 7.76 μM and a K i value of 4.39 μM.
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