TC-A 2317 hydrochloride

Overview

TC-A 2317 hydrochloride is an orally active Aurora A kinase inhibitor ( K i =1.2 nM). TC-A 2317 hydrochloride exhibits excellent selectivity to Aurora B kinase (K i =101 nM) and other 60 kinases, good cell permeability and good PK profile. Antitumor activity.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Aurora Kinase

Product Information

• Catalog No.: HY-103266
• CAS No.: 1245907-03-2
• Molecular Formula: C19H29ClN6O
• Molecular Weight: 392.93
• Purity: 99.57%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (6.36 mM); Clear solution
• Availability: In-stock

Source

Original product source