Neflamapimod

Overview

Neflamapimod (VX-745) is a potent, blood-brain barrier penetrant, highly selective inhibitor of p38α inhibitor with an IC 50 for p38α of 10 nM and for p38β of 220 nM. Neflamapimod (VX-745) possesses anti-inflammatory activity.

Application

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Product Information

• Catalog No.: HY-10328
• CAS No.: 209410-46-8
• Molecular Formula: C19H9Cl2F2N3OS
• Molecular Weight: 436.26
• Purity: 99.32%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 5 mg/mL (11.46 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source