NSC693868

Overview

NSC693868 is a selective inhibitor of CDK1 and CDK5 with IC 50 s of 600 nM and 400 nM, respectively. NSC693868 less potently inhibits GSK3β with an IC 50 of 1 µM) and does not block CDC25 activity. NSC693868 is used to help define the roles of CDK1 and CDK5 in various signaling pathways.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > CDK | Products > Signaling Pathways > GSK-3

Product Information

• Catalog No.: HY-103381
• CAS No.: 40254-90-8
• Molecular Formula: C9H7N5
• Molecular Weight: 185.19
• Purity: 99.0%
• Storage: -20°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Availability: In-stock

Source

Original product source