PD 168568 dihydrochloride is a orally active and potent dopamine receptor D 4 (DRD 4 ) antagonist. PD 168568 dihydrochloride contains an isoindolinone and is selective for the D 4 receptor versus D 2 and D 3 , with K i values of 8.8, 1842, and 2682 nM, respectively. PD 168568 dihydrochloride can be used for glioblastoma (GBM) research.
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