Fasudil

CAS No.：103745-39-7
Grade：99.98%
Formula：C14H17N3O2S
M.W.：291.37
Solvent：≥ 3.33 mg/mL (11.43 mM); Clear solution

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Overview

Fasudil (HA-1077; AT877) is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an K i of 0.33 μM for ROCK1 , IC 50 s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA , PKC , PKG , respectively. Fasudil is also a potent Ca 2+ channel antagonist and vasodilator.

Application

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Product Information

Catalog No.: HY-10341A
CAS No.: 103745-39-7
Molecular Formula: C14H17N3O2S
Molecular Weight: 291.37
Purity: 99.98%
Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Solubility: ≥ 3.33 mg/mL (11.43 mM); Clear solution
Availability: In-stock

Source

Original product source

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