Fasudil mesylate

Overview

Fasudil (HA-1077; AT877) mesylate is a nonspecific and orally active RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an K i of 0.33 μM for ROCK1 , IC 50 s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA , PKC , PKG , respectively. Fasudil mesylate is also a potent Ca 2+ channel antagonist and vasodilator.

Application

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Product Information

• Catalog No.: HY-10341D
• CAS No.: 1001206-62-7
• Molecular Formula: C15H21N3O5S2
• Molecular Weight: 387.47
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source