Vialinin A

Overview

Vialinin A (Terrestrin A) is a p-terphenyl compound that can be derived from a Chinese edible mushroom. Vialinin A is an inhibitor of ubiquitin-specific peptidase 4 ( USP4 ) and has anti-inflammatory and antioxidant properties. Vialinin A can alleviate cerebral ischaemia-reperfusion injury-induced neurological deficits and neuronal apoptosis . Vialinin A promotes activation of Keap1-Nrf2-ARE signaling pathway and increases the protein degradation of Keap1 . Vialinin A possesses various pharmacological activities in cancer , Kawasaki disease, asthma, and pathological scarring. Vialinin A is a potent inhibitor of TNF-α , USP4 , USP5 , and sentrin/SUMO-specific protease 1 ( SENP1 ). Vialinin A can be studied in reseach for autoimmune diseases, cancer and ischaemic stroke.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > NF-κB | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Deubiquitinase | Products > Signaling Pathways > TNF Receptor | Products > Signaling Pathways > E1/E2/E3 Enzyme | Products > Signaling Pathways > Keap1-Nrf2

Product Information

• Catalog No.: HY-103435
• CAS No.: 858134-23-3
• Molecular Formula: C34H26O8
• Molecular Weight: 562.57
• Purity: 99.90%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (4.44 mM); Clear solution
• Availability: In-stock

Source

Original product source