Desmethyl-YM-298198 is a high-affinity, selective, and noncompetitive mGluR1 antagonist ( IC 50 : 16 nM). Desmethyl-YM-298198 has analgesic effect in Streptozotocin ( HY-13753 )-induced hyperalgesic mice.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > mGluR
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