Naphthol AS-MX phosphate

Overview

Naphthol AS-MX phosphate (NASTRp) is a small molecule inhibitor of the CREB (cyclic adenosine phosphate reaction element binding protein)- CBP (CREB binding protein) transcription factor complex. Naphthol AS-MX phosphate shows antitumor activity against lung cancer cells, inhibiting tumor cell proliferation ( IC 50 =3.701 μmol/L), colony formation, and anchored independent growth in soft AGAR. Naphthol AS-MX phosphate can be used in the study of KRAS mutated lung cancer , especially for KRAS mutated lung cancer with poor chemotherapy resistance and prognosis.

Application

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Product Information

• Catalog No.: HY-104067
• CAS No.: 1596-56-1
• Molecular Formula: C19H18NO5P
• Molecular Weight: 371.32
• Purity: 99.50%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source