SKF-82958 ((±)-SKF 82958) hydrobromide is a dopamine D1 receptor full agonist (K 0.5 =4 nM), displays selective for D1 over D2 receptors (K 0.5 =73 nM). SKF-82958 hydrobromide induces dopamine D1 receptor-dependent adenylate cyclase activity in rat striatal membranes (EC 50 =491 nM).
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