PF-431396

Overview

PF-431396 is an orally active dual focal adhesion kinase ( FAK ) and proline-rich tyrosine kinase 2 ( PYK2 ) inhibitor, with IC 50 values of 2 nM and 11 nM, respectively.

Application

Products | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Lung Fibrosis | Products > Disease Areas > Cancer | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Pulmonary Disease | Products > Disease Areas > Pancreatic Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Pyk2 | Products > Signaling Pathways > FAK

Product Information

• Catalog No.: HY-10460
• CAS No.: 717906-29-1
• Molecular Formula: C22H21F3N6O3S
• Molecular Weight: 506.50
• Purity: 99.74%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (4.94 mM); Clear solution
• Availability: In-stock

Source

Original product source