Bretazenil

Overview

Bretazenil (Ro 16-6028) is a partial agonist at the gamma-aminobutyric acid A (GABA A ) receptor-linked benzodiazepine site. Bretazenil is potent benzodiazepine examined, exhibiting an IC 50 (concentration at which half-maximal inhibition of specific [35S]TBPS binding occurs) of 6.1 nM. Bretazenil shows an EC 50 of 10 nM for recombinant α1β1γ2. Anticonvulsant effects.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > GABA Receptor

Product Information

• Catalog No.: HY-105056
• CAS No.: 84379-13-5
• Molecular Formula: C19H20BrN3O3
• Molecular Weight: 418.28
• Purity: 99.13%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (5.98 mM); Clear solution
• Availability: In-stock

Source

Original product source