Avitriptan is a 5-HT 1B/1D receptor agonist, with pK i s of 7.44 ( 5-HT 1B rat), 7.68 ( 5-HT 1B human) and 8.36 ( 5-HT 1D human). Avitriptan constricts the isolated coronary artery. Avitriptan can be used for migraines.
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