BX795

Overview

BX795 is a potent and selective inhibitor of PDK1 , with an IC 50 of 6 nM. BX795 is also a potent and relatively specific inhibitor of TBK1 and IKKε , with an IC 50 of 6 and 41 nM, respectively. BX795 blocks phosphorylation of S6K1, Akt , PKCδ , and GSK3β, and has lower selectivity over PKA , PKC , c-Kit , GSK3β etc. BX795 modulates autophagy .

Application

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Product Information

• Catalog No.: HY-10514
• CAS No.: 702675-74-9
• Molecular Formula: C23H26IN7O2S
• Molecular Weight: 591.47
• Purity: 99.84%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (4.23 mM); Clear solution
• Availability: In-stock

Source

Original product source