CP-288886

Overview

CP-288886 is a cysLT 1 receptor antagonist with a K i value of 0.004 μM. CP-288886 exhibits comparable activity to Zafirlukast ( HY-17492 ) and Pranlukast ( HY-B0290 ). CP-288886 inhibits calcium mobilization with an IC 50 of 0.0005 μM in human U937 cells. CP-288886 has high oral bioavailability. CP-288886 possesses anti-asthmatic activity in a guinea pig asthma model and can be used for the research of diseases such as asthma.

Application

Products | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Leukotriene Receptor | Products > Signaling Pathways > Calcium Channel

Product Information

• Catalog No.: HY-105358
• CAS No.: 221332-74-7
• Molecular Formula: C30H28ClF3N2O6S
• Molecular Weight: 637.07
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source