GSK356278

Overview

GSK356278 is a potent, selective, orally bioavailable and brain-penetrant inhibitor of phosphodiesterase 4 ( PDE4 ) , with pIC 50 s of 8.6, 8.8, and 8.7 for human PDE4A, PDE4B, and PDE4D, respectively. GSK356278 has anti-inflammatory activity, and exhibits anxiolytic and cognition-enhancing effects.

Application

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Product Information

• Catalog No.: HY-106003
• CAS No.: 720704-34-7
• Molecular Formula: C21H25N7O2S
• Molecular Weight: 439.53
• Purity: 99.82%
• Storage: -20°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Solubility: ≥ 1.25 mg/mL (2.84 mM); Clear solution
• Availability: In-stock

Source

Original product source