SLV310 is an orally active dopamine D2 receptor antagonist ( K i : 5 nM) and serotonin reuptake receptor inhibitor. SLV310 antagonizes Apomorphine ( HY-12723 ) induced climbing behaviour and 5-HTP ( HY-N0122 ) induced serotonin syndrome like behaviour in mice (ED 50 : 5.6 and 5.9 mg/kg, p.o.). SLV310 is an antipsychotic compound and can be used for schizophrenia research.
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