Arimoclomol citrate

Overview

Arimoclomol citrate (BRX-220 citrate) is an orally active co-inducer of heat shock proteins ( HSP ). Arimoclomol citrate protects motor neurons by enhancing Hsp expression, thus directly affecting protein aggregation and clearance of misfolded assemblies via the proteasome-ubiquitin system. Arimoclomol citrate can be used for the study of Niemann–Pick disease type C.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Neurological Disease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > HSP

Product Information

• Catalog No.: HY-106443B
• CAS No.: 368860-21-3
• Molecular Formula: C20H28ClN3O10
• Molecular Weight: 505.90
• Purity: 99.76%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 5 mg/mL (9.88 mM); Clear solution
• Availability: In-stock

Source

Original product source