Etoperidone, an antidepressant agent, is an orally active serotonin and nor-adrenaline re-uptake antagonist. Etoperidone shows K d values of 36 nM, 38 nM, 85 nM, and 570 nM for 5-HT2 receptor , α1-adrenergic receptor , 5-HT1A receptor , and α2-adrenergic receptor , respectively.
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