Losigamone

Overview

Losigamone (AO-33) is an orally active antiepileptic compound. Losigamone blocks sodium channel . Losigamone stimulates the neuronal chloride channel and enhance chloride influx. Losigamone potentiates GABA-mediated responses and reduces epileptiform activity induced by chloride channel antagonists. Losigamone can be used for epilepsy research.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Sodium Channel | Products > Signaling Pathways > Chloride Channel

Product Information

• Catalog No.: HY-106822
• CAS No.: 112856-44-7
• Molecular Formula: C12H11ClO4
• Molecular Weight: 254.67
• Purity: 99.94%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (9.82 mM); Clear solution
• Availability: In-stock

Source

Original product source