Asoxime dimesylate

Overview

Asoxime dimesylate (HI-6 dimesylate) is an orally active thiosemicarbazone-based antidote. Asoxime dimesylate is a reversible inhibitor of AChE , and its core mechanism of action is to re-activate AChE inhibited by nerve toxins, thereby restoring the cholinergic nerve function. Asoxime dimesylate significantly restores the function of poisoned muscles without reactivating AChE . Asoxime dimesylate is an antagonist of acetylcholine receptors ( AChRs ), including nicotinic receptor and α7 nAChR . Asoxime dimesylate can serve as an effective immunomodulator, improving the immune effect of the nervous system.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurotrophic or Neurotoxic Disease | Products > Disease Areas > Neurotoxic Agent | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Cholinesterase (ChE) | Products > Signaling Pathways > nAChR

Product Information

• Catalog No.: HY-106901B
• CAS No.: 144252-71-1
• Molecular Formula: C16H22N4O9S2
• Molecular Weight: 478.50
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source