YM114

Overview

YM114 (KAE-393) is a highly potent and selective (5-HT) 3 -receptor antagonist that does not affect Veratridine ( HY-N6691 )- or electrical stimulation-induced bradycardia in anesthetized rats. YM114 inhibits 2-methyl-5-HT ( HY-19358 )-induced Bezold-Jarisch reflex, which originates from (5-HT) 3 -receptor located on the endings of vagal afferent nerves in the heart.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > 5-HT Receptor

Product Information

• Catalog No.: HY-106909A
• CAS No.: 153608-99-2
• Molecular Formula: C16H18ClN3O
• Molecular Weight: 303.79
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source