SG-210

Overview

SG-210 (SPR 210) is an orally active and selective aldose reductase ( AR ) inhibitor. SG-210 has IC 50 values of 9.5 nM and 10 nM for AR from porcine lens and human placenta, respectively. SG-210 can inhibit sorbitol accumulation and ameliorate diabetic neuropathy and retinopathy in Streptozotocin ( HY-13753 )-induced diabetic rats. SG-210 can be used in the research of diseases such as diabetes-related complications.

Application

Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Aldose Reductase

Product Information

• Catalog No.: HY-106915
• CAS No.: 143162-65-6
• Molecular Formula: C18H11F3N2O3S2
• Molecular Weight: 424.42
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source