NSC12

Overview

NSC12 is an orally active pan- FGF trap. NSC12 inhibits the interaction between FGF2/FGFR . NSC12 suppresses the phosphorylation of FGFR3 . NSC12 reduces c-Myc levels, induces DNA damage, triggers the cleavage of Caspase 3 , and promotes ROS production. NSC12 exhibits anticancer activity against lung cancer and multiple myeloma.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Lung Cancer | Products > Disease Areas > Blood Disease | Products > Disease Areas > Multiple Myeloma | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > DNA/RNA Synthesis | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > FGFR | Products > Signaling Pathways > c-Myc

Product Information

• Catalog No.: HY-107194
• CAS No.: 102586-30-1
• Molecular Formula: C24H34F6O3
• Molecular Weight: 484.52
• Purity: 99.98%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source