TC-N 1752

Overview

TC-N 1752 is a potent and orally active inhibitor of Nav1.7 , with IC 50 s of 0.17 μM, 0.3 μM, 0.4 μM, 1.1 μM and 2.2 μM at hNav1.7 , hNav1.3 , hNav1.4 , hNaV1.5 and rNav1.8 , respectively. TC-N 1752 also inhibits tetrodotoxin-sensitive sodium channels. TC-N 1752 shows analgesic efficacy in the Formalin model of pain.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Sodium Channel

Product Information

• Catalog No.: HY-107405
• CAS No.: 1211866-85-1
• Molecular Formula: C25H27F3N6O3
• Molecular Weight: 516.52
• Purity: 99.67%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source