GNE 5729

Overview

GNE 5729 is a brain permeable positive allosteric modulator of NMDAR , with an EC 50 of 37 nM for GluN2A, 4.7 and 9.5 μM for GluN2C and GluN2D, respectively.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > iGluR

Product Information

• Catalog No.: HY-107409
• CAS No.: 2026635-66-3
• Molecular Formula: C17H10Cl2F3N5O
• Molecular Weight: 428.20
• Purity: 99.05%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (5.84 mM); Clear solution
• Availability: In-stock

Source

Original product source