Hypothemycin, a fungal polyketide, is a multikinase inhibitor with K i s of 10/70 nM, 17/38 nM, 90 nM, 900 nM/1.5 μM, and 8.4/2.4 μM for VEGFR2/VEGFR1 , MEK1/MEK2 , FLT-3 , PDGFRβ/PDGFRα , and ERK1/ERK2 , respectively.
Products | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > VEGFR | Products > Signaling Pathways > MEK | Products > Signaling Pathways > FLT3 | Products > Signaling Pathways > PDGFR | Products > Signaling Pathways > ERK
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