UBP 1112 is a selective group III mGluR antagonist, with a K d of 5.1 μM.UBP 1112 shows 96-fold affinity for group III over group II mGlu receptor ( K d , 488 μM), and shows no significant activity at group I mGlu receptor or iGlu receptor.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > mGluR
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