TC-MCH 7c, a phenylpyridone derivative, is an orally available, selective and brain-penetrable MCH 1 R antagonist with an IC 50 of 5.6 nM for hMCH 1 R. TC-MCH 7c has K i s of 3.4 nM and 3.0 nM of human and mouse MCH 1 R, respectively.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > MCHR1 (GPR24)
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