(S)-(+)-Dimethindene maleate

Overview

(S)-(+)-Dimethindene maleate, an enantiomer, is a potent M 2 -selective muscarinic receptor antagonist ( pA 2 = 7.86/7.74; pK i = 7.78). (S)-(+)-Dimethindene maleate shows lower affinities for the muscarinic M 1 (pA 2 = 6.83/6.36; pK i = 7.08), the M 3 (pA 2 = 6.92/6.96; pK i = 6.70) and the M 4 receptors (pK i = 7.00), respectively. (S)-(+)-Dimethindene maleate also is a histamine H 1 receptor antagonist ( pA 2 = 7.48).

Application

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Product Information

• Catalog No.: HY-107647
• CAS No.: 136152-65-3
• Molecular Formula: C24H28N2O4
• Molecular Weight: 408.49
• Purity: 99.80%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2 mg/mL (4.90 mM); Clear solution
• Availability: In-stock

Source

Original product source