Clodronate disodium tetrahydrate

Overview

Clodronate disodium tetrahydrate (Disodium clodronate tetrahydrate) is first-generation bisphosphonate, with anti-osteoporotic, anti-inflammatory and analgesic effects. Clodronate disodium tetrahydrate is a selective, potent, reversible and Cl - competitive vesicular nucleotide transporter (VNUT) inhibitor, with an IC 50 of 15.6 nM. Clodronate disodium tetrahydrate inhibits vesicular ATP release from neurons and reduces chronic neuropathic and inflammatory pain.

Application

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Product Information

• Catalog No.: HY-107794
• CAS No.: 88416-50-6
• Molecular Formula: CH10Cl2Na2O10P2
• Molecular Weight: 360.92
• Purity: 99.86%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: 25 mg/mL (69.27 mM); Clear solution; Need ultrasonic and warming
• Availability: In-stock

Source

Original product source