R59949

Overview

R59949 is a pan diacylglycerol kinase ( DGK ) inhibitor with an IC 50 of 300 nM. R59949 strongly inhibits the activity of type I DGK α and γ and moderately attenuates the activity of type II DGK θ and κ. R59949 activates protein kinase C ( PKC ) by enhancing the levels of the endogenous ligand diacyl glycerol.

Application

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Product Information

• Catalog No.: HY-108355
• CAS No.: 120166-69-0
• Molecular Formula: C28H25F2N3OS
• Molecular Weight: 489.58
• Purity: 99.98%
• Storage: -20°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (5.11 mM); Clear solution
• Availability: In-stock

Source

Original product source