SB-277011 dihydrochloride (SB-277011A dihydrochloride) is a potent, selective, orally bioavailable and brain penetrate dopamine D 3 receptor antagonist, with pK i s of 8.0, 6.0, <5.2 and 5.9 for D 3 , D 2 , 5-HT 1B , and 5-HT 1D receptors, respectively.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Dopamine Receptor
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