MG-115

MG-115
  • CAS No.:133407-86-0
  • Grade:99.61%
  • Formula:C25H39N3O5
  • M.W.:461.59
  • Solvent:≥ 6.25 mg/mL (13.54 mM); Clear solution

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

Overview

MG-115 is a potent and reversible proteasome inhibitor, with K i s of 21 nM and 35 nM for 20S and 26S proteasome , respectively. MG-115 specifically inhibit the chymotrypsin-like activity of the proteasome , induces p53-dependent apoptosis .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Proteasome | Products > Signaling Pathways > Apoptosis

Product Information

  • Catalog No.: HY-108552
  • CAS No.: 133407-86-0
  • Molecular Formula: C25H39N3O5
  • Molecular Weight: 461.59
  • Purity: 99.61%
  • Storage: -20°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
  • Solubility: ≥ 6.25 mg/mL (13.54 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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