XE991

Overview

XE 991 dihydrochloride, a Kv7 (KCNQ) channels blocker, potently inhibits Kv7.1 (KCNQ1) , Kv7.2 (KCNQ2) , Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current with IC 50 s of 0.75 μM, 0.71 μM, 0.6 μM, and 0.98 μM, respectively.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Alzheimer's Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Potassium Channel

Product Information

• Catalog No.: HY-108577A
• CAS No.: 122955-42-4
• Molecular Formula: C26H20N2O
• Molecular Weight: 376.45
• Purity: 99.69%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (6.64 mM); Clear solution
• Availability: In-stock

Source

Original product source