JJKK 048 is a highly selective and potent monoacylglycerol lipase ( MAGL ) inhibitor with IC 50 values of 214 pM, 275 pM and 363 pM for human, rat, and mouse MAGL . JJKK 048 displays low cross-reactivity with other endocannabinoid targets. JJKK 048 can be used in the research of diseases such as cancer , neurodegenerative diseases, and pain.
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