SHA 68 is a potent and selective non-peptide neuropeptide S receptor (NPSR) antagonist with IC 50 s of 22.0 and 23.8 nM for NPSR Asn 107 and NPSR Ile 107 , respectively. SHA 68 has limited the blood-brain barrier (BBB) penetration and the activity in neuralgia.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Neuropeptide S Receptor
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