SU16f

Overview

SU16f is a potent and selective PDGFRβ inhibitor with IC 50 s of 10 nM, 140 nM, 2.29 μM for PDGFRβ , VEGF-R2, FGF-R1, respectively. Neutralization of PDGFRβ receptor by SU16f blocks the promoting role of GC-MSCs (gastric cancer-derived mesenchymal stem cells) conditioned medium in gastric cancer cell proliferation and migration.

Application

Products | Products > Disease Areas > Liver Cancer | Products > Disease Areas > Lung Fibrosis | Products > Disease Areas > Cancer | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Pulmonary Disease | Products > Disease Areas > Gastric Cancer | Products > Disease Areas > Digestive System Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Signaling Pathways > PDGFR

Product Information

• Catalog No.: HY-108628
• CAS No.: 251356-45-3
• Molecular Formula: C24H22N2O3
• Molecular Weight: 386.44
• Purity: 99.36%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 2.5 mg/mL (6.47 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source