PSB 0474

Overview

PSB 0474 (3-phenacyl-UDP) is a UDP ( HY-113359 ) analog and selective P2Y 6 receptor agonist, with an EC 50 value of 70 nM for the hP2Y 6 receptor. PSB 0474 activates Phospholipase C -coupled receptors to increase intracellular inositol phosphate levels. PSB 0474 enhances NO release by upregulating inducible iNOS and induces Apoptosis . PSB 0474 increases micturition frequency in urine of anesthetized rats, without altering bladder contraction amplitude/duration or causing urothelial damage. PSB 0474 can be used in studies related to chronic brain inflammation.

Application

Products | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Urologic Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Neurological Disease | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Endocrinology | Products > Signaling Pathways > Phospholipase | Products > Signaling Pathways > NO Synthase | Products > Signaling Pathways > P2Y Receptor | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Drug Derivative

Product Information

• Catalog No.: HY-108654
• CAS No.: 917567-60-3
• Molecular Formula: C17H20N2O13P2
• Molecular Weight: 522.29
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source