NF110 is a P2X 3 receptor antagonist ( K i = 36 nM) and inactive toward P2Y receptors stably expressed (IC 50 s > 10 M). NF110 blocks alphabeta-methylene-ATP-induced currents (IC 50 = 527 nM) in rat dorsal root ganglia neurons.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > P2X Receptor
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