A-620223 succinate (ABT-472) is an orally available poly(ADP-ribose) polymerase ( PARP ) inhibitor. A-620223 succinate (ABT-472) exhibits very good potency against the PARP-1 enzyme with a K i value of 8 nM and an EC 50 value of 3 nM in whole cell assay, making it useful in cancer research.
Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PARP
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